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Safety Profile

Traumeel and Zeel Injection Solutions were developed by physicians in Europe and have been available globally, for more than sixty years. Using very low doses of plant and mineral extracts, Traumeel and Zeel Injection Solutions help manage the pain, inflammation and joint degeneration of arthritis and osteoarthritis while exhibiting an excellent safety profile:

  • Not affecting blood glucose levels
  • Safe for cardiovascular risk patients
  • Can be injected without limitation of frequency
  • Safe to be injected near to tendon structures
  • Non-Narcotic, non-Addictive
  • No known drug interactions - Easy to combine with other medications

In vitro studies

An in vitro study has shown that neither the ingredients of Traumeel Injection Solution, nor Traumeel Injection Solution itself, are cytotoxic to granulocytes, lymphocytes, platelets and endothelia. This indicates that the defensive functions of these cells are preserved during treatment with Traumeel Injection Solution.

Adverse effects

Adverse effects with Traumeel Injection Solution are extremely rare. Traumeel Injection Solution exhibits no known adverse renal, hepatic, cardiovascular, gastrointestinal or central nervous system effects.

Hypersensitivity reactions can occur in individual cases. Skin rash and pruritus and, in rare cases, facial swelling, dyspnea, dizziness and a fall in blood pressure have been observed after treatment with products containing Echinacea extracts.

In rare cases, patients with hypersensitivity to botanicals of the Compositae family may experience an allergic reaction after the administration of Traumeel Injection Solution, including an anaphylactic reaction.

Drug interactions

There are no known drug interactions with Traumeel Injection Solution and other medications or molecules, and Traumeel Injection Solution is not known to interact with any laboratory tests. No studies have been performed to evaluate the carcinogenicity of Traumeel Injection Solution. However, in worldwide post-marketing surveillance studies, no evidence of carcinogenicity has been found (Data on file. Biologische Heilmittel Heel GmbH, Baden-Baden, Germany.)

Table 1: Overview of typical precautions and warnings for Traumeel® Injections Solution, Corticosteroid injections and oral NSAIDs. Sources: Package inserts of Traumeel Injection Solution2, betamethasone (Corticosteroid injection)3 and naproxen (NSAID oral)4


1 Porozov S, Cahalon L, Weiser M, Branski D, Lider O, Oberbaum M. Inhibition of IL-1ß and TNF-a Secretion from Resting and Activated Human Immunocytes by the Homeopathic Medication Traumeel S. Clin Dev Immunol. 2004;11(2):143-149.